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Medication Strattera with active ingredient Atomoxetine is a highly potent inhibitor of presynaptic norepinephrine transporters. Preparation has minimal affinity for adrenoceptors or other neurotransmitter receptors or transporters. Pharmacokinetics in children and adolescents is similar with adults.

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Usually doctors assign Strattera generic for attention deficit hyperactivity disorder (ADHD) in adults, adolescents and children of 6 years. Medicament is taken orally with meals or whatever the diet, 1 times a day, in the morning. The capsules are not intended for dissection. If you cancel Strattera medication the gradual dose reduction is required. For children and adolescents with a body weight up to 70 kg the optimal initial daily dose is 500 mcg / kg and increased to a therapeutic daily dose of 1.2 mg / kg (not earlier than 3 days). The recommended maintenance dosage is about 1.2 mg by kg body weight per day. Teenagers and children with body weight more than 70 kg, as well as for adults take daily 40 mg, and increased up to the therapeutic daily dosing about 80 mg (no earlier than 3 days). Patients can study all information about dosages of medicament in its instructions.

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Contra-indications to the appointment of medicine are:

  • severe heart disease;
  • the combined use with MAO inhibitors;
  • angle-closure glaucoma;
  • individual hypersensitiveness to the auxiliary components.

Strattera is prescribed with extreme caution in patients with hypertension, cardiovascular disease, tachycardia, during heavy physical overload, cerebrovascular accident, a family history of sudden cardiac death and seizures, while the use of stimulants, as well as in conditions involving arterial hypotension . The use of generic for Strattera in teenagers and children can cause the following adverse reactions as:

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  • sinus tachycardia, palpitations, orthostatic hypotension;
  • abdominal pain, vomiting, loss of appetite;
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  • rash, dermatitis; sometimes – itching;
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Generic Strattera should be assigned with caution in patients receiving beta2-agonists, as it may intensify their effects on the cardiovascular system. Due to the possible effect on blood pressure medicine should be applied with caution in combination with antihypertensive or vasopressor agents, and other agents capable to raise blood pressure. It must not be taken for at least 2 weeks after discontinuation of MAOIs

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The most common signs in acute or chronic overdose when is Strattera going generic are the symptoms of the digestive system, sleepiness, dizziness, tremor, and conduct disorder, seizures. It is also reported on strengthening the development of hyperactivity and excitement. There were signs of mild or moderate increase in activity of the sympathetic nervous system (such as tachycardia, dilated pupils, dry mouth). It is recommended to provide ventilation, to monitor cardiac and vital signs, and symptomatic and supportive treatment.

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