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Medicine Tramadol is a synthetic opioid, has a pronounced analgesic (painkiller) effect. Action is due to its agonist effects on the CNS opioid receptors. According to instructions for the preparation Tramadol online refers to pain relief the central mechanism of action. The effect of its reception occurs quite rapidly (within 30 minutes after administration) and lasts 5 hours.
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Humans in general buy Tramadol online for acute and chronic severe pain of various etiology: post-traumatic and post-operative pain, pain in oncology. The medicant is only used in medium and severe pain, and is not recommended for milder forms of pain. Also, a drug is applied for pain syndromes in neurology, dentistry, orthopedics, obstetrics. Doses are selected individually (depending on the severity of pain and the sensitivity of the patient). The therapy duration is also determined personally, but it should not be prescribed the beyond the period justified from a therapeutic point of view. Adults and adolescents over 14 years of age take the usual dose Tramadol 50mg tablets with a small amount of liquid. If necessary, in case of lack of effect 30-60 minutes after reception it can be repeated at the same dosage, but not more than 8 doses per day. The maximum daily dosing is 0.4 g (400 mg). Effect lasts 4-8 hours on average, depending on the nature and intensity of pain.
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Contraindications and adverse reactions under using Tramadol product no rx
Tramadol medicine is contraindicative if:
- acute alcohol poisoning or the means oppressive central nervous system;
- liver and kidney functions;
- hildren under 14 years.
Remedy is relatively well tolerated, and if you purchase Tramadol online at therapeutic doses does not cause respiratory depression and expressed essentially no effect on the circulatory system and gastrointestinal tract. It may, however, invoke:
- decreased cognitive ability;
- epigastric pain;
- difficulty urinating.
The frequency of side effects increases with the duration of treatment.
What are Tramadol medicine interactions with various medications without prescription?
Preparation enhances the effects of hypnotics, sedatives and anesthetic drugs, anxiolytics, alcohol. In combination with neuroleptics and MAO inhibitors remedy increases the risk of epileptiform convulsions. In patients receiving long-term carbamazepine, Tramadol tablets metabolism is greatly enhanced, which may require increased doses of analgesic. The medicament should not be combined with narcotic analgesics from the group of complete or partial agonists, and agonist-antagonists opioid receptors. Inductors of microsomal oxidation (Carbamazepine, barbiturates) reduce the duration of the analgesic effect. Long-term use of opioid analgesics and barbiturates stimulates the development of cross-tolerance.
Can people overdose on tablets of Tramadol with application no prescription?
For the use of high doses of Tramadol pain medicine there may be the following symptoms as vomiting, collapse, cramps, convulsions, coma, and central nervous system depression. Treatment will include airway, maintaining adequate pulmonary ventilation, maintenance of the cardiovascular system, symptomatic therapy. In chronic poisoning there is possible development of abstinent syndrome.
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